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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 178516Generated: October 26, 2026

Tetrahydrofuran → (6-{2-[4-Cyclopropyl-2-(4-trifluoromethyl-phenyl)-pyrimidin-5-yl]-ethoxy}-indol-1-yl)-acetic acid ethyl ester

https://huagongshe.com/reaction/178516

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantTriphenylphosphineHCID 11776—
ReactantDi-tert-butyl azodicarboxylateHCID 97268—
Reactant2-[4-Cyclopropyl-2-(4-trifluoromethyl-phenyl)-pyrimidin-5-yl]-ethanolHCID 22250819—
Reactant(6-Hydroxy-indol-1-yl)-acetic acid ethyl esterHCID 68821422—
Product(6-{2-[4-Cyclopropyl-2-(4-trifluoromethyl-phenyl)-pyrimidin-5-yl]-ethoxy}-indol-1-yl)-acetic acid ethyl esterHCID 69641848—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (6/10)
ORD IDord-03930f6fa20943528e4501e862bd5a67
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (6/10)