HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 54153445, compound → Methyl 3-(4-Hydroxy-2-methylphenyl)propanoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 54153445 | HCID 54153445 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | Methyl 3-(4-Hydroxy-2-methylphenyl)propanoate | HCID 13551833 | 93.5% |
Reaction Steps
A mixture of 3-(4-Benzyloxy-2-methyl-phenyl)-propionic acid methyl ester (13.7 g, 48.5 mmol) and Pd/C (5%, 13.7 g) in MeOH (423 mL) is stirred under 60 psi of hydrogen for 24 hrs. Catalyst is filtered off, filtrate is concentrated giving the title compound (8.8 g, 93.5%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07504433B2 |
| Source dataset | uspto-grants-2009_03 |
| ORD ID | ord-25921e698a2b4805b0570971a8e2cd08 |
| Source note | uspto-grants-2009_03 |