Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1785449Generated: October 31, 2026

HCID 69066824, compound → HCID 86600377, compound

https://huagongshe.com/reaction/1785449

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 69066824HCID 69066824—
CatalystHCID 178418406HCID 178418406—
SolventDichloromethaneHCID 6344—
ProductHCID 86600377HCID 86600377—

Reaction Steps

The mixture of 1-{2-[2-(4-hydroxymethyl-phenyl)-1-methyl-ethylamino]-pyrimidin-4-yl}-8-phenyl-1,2,3,6-tetrahydro -pyrimido[1,2-a]pyrimidin-4-one (0.38 g, 0.81 mmol) and manganese dioxide (3.5 g, 40.5 mmol) in dichloromethane was stirred at room temperature for 3 h. The mixture was filtered off and concentrated to afford a white solid. M+1=467.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07504403B2
Source datasetuspto-grants-2009_03
ORD IDord-6de1fbcc324e4549a960abe50ca5c371
Source noteuspto-grants-2009_03