反应详情

Followed the same procedure described for the synthesis of 1-(2-phenethylamino-pyrimidin-4-yl)-8-phenyl-1,2,3,4-tetrahydro -pyrido[1,2-a]pyrimidin-6-one, the sulfoxide (0.22 g, 0.6 mmol) was displaced with 2-(2-chlorophenyl)ethylamine (0.25 mL, 1.8 mmol) to give the title compound as a yellow solid. MS m/e 458 (M+H)+.