Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
m-Toluohydrazide → 3-Methyl-benzoic acid N'-[4-(3-chloro-phenyl)-2-(5,6-dimethoxy-benzoimidazol-1-yl)-thiazole-5-carbonyl]-hydrazide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | m-Toluohydrazide | HCID 83082 | — |
| 반응물 | 4-(3-Chloro-phenyl)-2-(5,6-dimethoxy-benzoimidazol-1-yl)-thiazole-5-carboxylic acid | HCID 23654019 | — |
| 생성물 | 3-Methyl-benzoic acid N'-[4-(3-chloro-phenyl)-2-(5,6-dimethoxy-benzoimidazol-1-yl)-thiazole-5-carbonyl]-hydrazide | HCID 23654550 | 3.8% |
반응 단계
In a similar manner as described for Example 53, 4-(3-Chloro-phenyl)-2-(5,6-dimethoxy-benzoimidazol-1-yl)-thiazole-5-carboxylic acid (41 mg, 0.1 mmol) and m-toluic acid hydrazide (15.0 mg, 0.1 mmol, Lancaster) gave 3-Methyl-benzoic acid N′-[4-(3-chloro-phenyl)-2-(5,6-dimethoxy-benzoimidazol-1-yl)-thiazole-5-carbonyl]-hydrazide (2.1 mg, 3.8%) as a white solid. MS m/z 548 (M+1).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07504513B2 |
| 출처 데이터셋 | uspto-grants-2009_03 |
| ORD ID | ord-a9b9f7be58f945379c7e2def803e8dae |
| 출처 메모 | uspto-grants-2009_03 |