HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(3-Chloro-phenyl)-2-(5,6-dimethoxy-benzoimidazol-1-yl)-thiazole-5-carboxylic acid → HCID 178486841, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(3-Chloro-phenyl)-2-(5,6-dimethoxy-benzoimidazol-1-yl)-thiazole-5-carboxylic acid | HCID 23654019 | — |
| Reactant | Cytosine | HCID 178418229 | — |
| Product | HCID 178486841 | HCID 178486841 | 11% |
Reaction Steps
In a similar manner as described for Example 53, 4-(3-Chloro-phenyl)-2-(5,6-dimethoxy-benzoimidazol-1-yl)-thiazole-5-carboxylic acid (41 mg, 0.1 mmol) and cytosine (11.1 mg, 0.1 mmol, Aldrich) gave 4-(3-Chloro-phenyl)-2-(5,6-dimethoxy-benzoimidazol-1-yl)-thiazole-5-carboxylic acid (2-oxo-1,2-dihydro-pyrimidin-4-yl)-amide (5.6 mg, 11.0%) as a white solid. MS m/z 509 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07504513B2 |
| Source dataset | uspto-grants-2009_03 |
| ORD ID | ord-cdfd204a5bc24d5ca42307623e861556 |
| Source note | uspto-grants-2009_03 |