HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Bromo-2-(5,6-dimethoxy-benzoimidazol-1-yl)-thiazole-5-carboxylic acid methyl ester → HCID 23654382, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Bromo-2-(5,6-dimethoxy-benzoimidazol-1-yl)-thiazole-5-carboxylic acid methyl ester | HCID 57595851 | — |
| Reactant | HCID 68828138 | HCID 68828138 | — |
| Product | HCID 23654382 | HCID 23654382 | 46.4% |
Reaction Steps
In a similar manner as described for Example 26, 4-bromo-2-(5,6-dimethoxy-benzoimidazol-1-yl)-thiazole-5-carboxylic acid methyl ester (120 mg, 0.3 mmol) and 2-chloropyridine-2-boronic acid (71 mg, 0.45 mmol) gave 4-(2-Chloro-pyridin-4-yl)-2-(5,6-dimethoxy-benzoimidazol-1-yl)-thiazole-5-carboxylic acid (58 mg, 46.4%) as a white solid. MS 417 m/z (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07504513B2 |
| Source dataset | uspto-grants-2009_03 |
| ORD ID | ord-99e207888bd243beabf304f07f498f58 |
| Source note | uspto-grants-2009_03 |