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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1785545Generated: October 25, 2026

N-(7-ethoxy-5,8-dihydronaphthalen-1-yl)-5-[4-(trifluoromethyl)phenyl]-1,3-oxazol-2-amine → 8-{[5-(4-bromophenyl)-1,3-oxazol-2-yl]amino}-3,4-dihydronaphthalen-2(1H)-one

https://huagongshe.com/reaction/1785545

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-(7-ethoxy-5,8-dihydronaphthalen-1-yl)-5-[4-(trifluoromethyl)phenyl]-1,3-oxazol-2-amineHCID 67229299—
Reactant5-(4-bromophenyl)-N-(7-ethoxy-5,8-dihydronaphthalen-1-yl)-1,3-oxazol-2-amineHCID 67229810—
Product8-{[5-(4-bromophenyl)-1,3-oxazol-2-yl]amino}-3,4-dihydronaphthalen-2(1H)-oneHCID 11964235—

Reaction Steps

The title compound was prepared using the procedure as described in Example 1I, substituting the product of Example 8B for the product of Example 1H.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07504520B2
Source datasetuspto-grants-2009_03
ORD IDord-3efeac350b1f49f39269681ba7eceaf9
Source noteuspto-grants-2009_03