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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1785557Generated: October 30, 2026

8-{5-[4-(Trifluoromethyl)phenyl]oxazol-2-ylamino}-3,4-dihydronaphthalen-2(1H)-one → HCID 11964285, compound

https://huagongshe.com/reaction/1785557

Reaction equation

Participants

RoleNameHCIDCharge
Reactant8-{5-[4-(Trifluoromethyl)phenyl]oxazol-2-ylamino}-3,4-dihydronaphthalen-2(1H)-oneHCID 11955840—
ReactantHCID 11964239HCID 11964239—
ProductHCID 11964285HCID 11964285—

Reaction Steps

The title compound was prepared using the procedure as described in Example 2, substituting the product of Example 15C for the product of Example 1I. 1H NMR (DMSO-d6) δ 9.08 (s, 1H), 7.58 (d, 1H, J=7.3 Hz), 7.26-7.39 (m, 4H), 7.04-7.12 (m, 2H), 6.83 (d, 1H, J=7.2 Hz), 4.81 (d, 1H, J=4.1 Hz), 3.93 (m, 1H), 2.73-2.97 (m, 4H), 2.33 (s, 3H), 1.86 (m, 1H), 1.61 (m, 1H); MS (ESI+) m/z 321 (M+H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07504520B2
Source datasetuspto-grants-2009_03
ORD IDord-f483c9fe863e4f228bd6307a1ed68794
Source noteuspto-grants-2009_03