Isocyanate → 3-(4,4'-dichlorobenzhydryloxy)-N-(2,4-dichlorobenzyl)azetidine-1-carboxamide

HRID 1785641Notes

Reaction equation

HRID 1785641 reaction equation
[Cl:1][C:2]1[CH:20]=[CH:19][C:5]([CH:6]([O:14][CH:15]2[CH2:18][NH:17][CH2:16]2)[C:7]2[CH:12]=[CH:11][C:10]([Cl:13])=[CH:9][CH:8]=2)=[CH:4][CH:3]=1.[N-:21]=[C:22]=[O:23].[Cl:24][C:25]1[CH:50]=[C:49]([Cl:51])[CH:48]=[CH:47][C:26]=1[CH:27](OC1CN(C(NC(C)(C)C)=O)C1)C1C=CC(Cl)=CC=1>>[Cl:1][C:2]1[CH:20]=[CH:19][C:5]([CH:6]([O:14][CH:15]2[CH2:18][N:17]([C:22]([NH:21][CH2:27][C:26]3[CH:47]=[CH:48][C:49]([Cl:51])=[CH:50][C:25]=3[Cl:24])=[O:23])[CH2:16]2)[C:7]2[CH:8]=[CH:9][C:10]([Cl:13])=[CH:11][CH:12]=2)=[CH:4][CH:3]=1

Participants

4

Reactant 3

HCID 105034IsocyanateHCID 114420773-(2,4,4'-trichlorobenzhydryloxy)-N-(tert-butyl)azetidine-1-carboxamideHCID 689061393-(4,4'-Dichlorobenzhydryloxy)azetidine

Product 1

HCID 689037833-(4,4'-dichlorobenzhydryloxy)-N-(2,4-dichlorobenzyl)azetidine-1-carboxamide

Procedure

This material was prepared from 3-(4,4′-dichlorobenzhydryloxy)azetidine (36) and the corresponding commercially available isocyanate, using the procedure described for compound (5).

Sources & evidence

ORD record
ord-5e223a82346f4250829716df2fd26b68
Source dataset
uspto-grants-2009_03
Patent number
US07504522B2

Reaction notes

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