3-(2,4'-Dichlorobenzhydryloxy)azetidine hydrochloride → 3-(2,2'-Dichlorobenzhydryloxy)azetidine hydrochloride

HRID 1785645Notes

Reaction equation

HRID 1785645 reaction equation
C([N:14]1[CH2:17][CH:16]([O:18][CH:19]([C:27]2[CH:32]=[CH:31][CH:30]=[CH:29][C:28]=2[Cl:33])[C:20]2[CH:25]=[CH:24][CH:23]=[CH:22][C:21]=2[Cl:26])[CH2:15]1)(C1C=CC=CC=1)C1C=CC=CC=1.Cl.ClC1C=CC=CC=1C(OC1CNC1)C1C=CC(Cl)=CC=1>>[ClH:26].[Cl:33][C:28]1[CH:29]=[CH:30][CH:31]=[CH:32][C:27]=1[CH:19]([O:18][CH:16]1[CH2:17][NH:14][CH2:15]1)[C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][C:21]=1[Cl:26]

Participants

3

Reactant 2

HCID 689023433-(2,4'-Dichlorobenzhydryloxy)azetidine hydrochlorideHCID 689062321-Benzhydryl-3-(2,2'-dichlorobenzhydryloxy)azetidine

Product 1

HCID 689078523-(2,2'-Dichlorobenzhydryloxy)azetidine hydrochloride

Procedure

This material was prepared from compound (67) (12.7 mmol) using the procedure described for compound (9) (1.58 g, 48%).

Sources & evidence

ORD record
ord-988f5476f69b4b66bb74ad3a905820c9
Source dataset
uspto-grants-2009_03
Patent number
US07504522B2

Reaction notes

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