Isocyanate → 3-(2,2'-dichlorobenzhydryloxy)-N-(sec-butyl)azetidine-1-carboxamide

HRID 1785648Notes

Reaction equation

HRID 1785648 reaction equation
Cl.Cl[C:3]1C=CC=CC=1C(OC1CNC1)C1C=CC=CC=1Cl.[N-]=C=O.[Cl:25][C:26]1[CH:51]=[CH:50][CH:49]=[CH:48][C:27]=1[CH:28]([O:36][CH:37]1[CH2:40][N:39]([C:41]([NH:43][C:44]([CH3:47])([CH3:46])C)=[O:42])[CH2:38]1)[C:29]1[CH:34]=[CH:33][CH:32]=[CH:31][C:30]=1[Cl:35]>>[Cl:35][C:30]1[CH:31]=[CH:32][CH:33]=[CH:34][C:29]=1[CH:28]([O:36][CH:37]1[CH2:38][N:39]([C:41]([NH:43][CH:44]([CH2:46][CH3:3])[CH3:47])=[O:42])[CH2:40]1)[C:27]1[CH:48]=[CH:49][CH:50]=[CH:51][C:26]=1[Cl:25]

Participants

4

Reactant 3

HCID 105034IsocyanateHCID 689024333-(2,2'-dichlorobenzhydryloxy)-N-(tert-butyl)azetidine-1-carboxamideHCID 689078523-(2,2'-Dichlorobenzhydryloxy)azetidine hydrochloride

Product 1

HCID 689031983-(2,2'-dichlorobenzhydryloxy)-N-(sec-butyl)azetidine-1-carboxamide

Procedure

This material was prepared from 3-(2,2′-dichlorobenzhydryloxy)azetidine hydrochloride (68) and the corresponding commercially available isocyanate using the procedure described for compound (69).

Sources & evidence

ORD record
ord-2f397704ad47411c95b75c324b6141df
Source dataset
uspto-grants-2009_03
Patent number
US07504522B2

Reaction notes

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