3-(2,4'-Dichlorobenzhydryloxy)azetidine hydrochloride → 3-(Bis(4-bromophenyl)methoxy)azetidine hydrochloride

HRID 1785657Notes

Reaction equation

HRID 1785657 reaction equation
C([N:14]1[CH2:17][CH:16]([O:18][CH:19]([C:27]2[CH:32]=[CH:31][C:30]([Br:33])=[CH:29][CH:28]=2)[C:20]2[CH:25]=[CH:24][C:23]([Br:26])=[CH:22][CH:21]=2)[CH2:15]1)(C1C=CC=CC=1)C1C=CC=CC=1.Cl.[Cl:35]C1C=CC=CC=1C(OC1CNC1)C1C=CC(Cl)=CC=1>>[ClH:35].[Br:26][C:23]1[CH:24]=[CH:25][C:20]([CH:19]([O:18][CH:16]2[CH2:17][NH:14][CH2:15]2)[C:27]2[CH:28]=[CH:29][C:30]([Br:33])=[CH:31][CH:32]=2)=[CH:21][CH:22]=1

Participants

3

Reactant 2

HCID 689023433-(2,4'-Dichlorobenzhydryloxy)azetidine hydrochlorideHCID 689034371-Benzhydryl-3-(4,4'-dibromobenzhydryloxy)azetidine

Product 1

HCID 689060933-(Bis(4-bromophenyl)methoxy)azetidine hydrochloride

Procedure

This material was prepared from 1-benzhydryl-3-(4,4′-dibromobenzhydryloxy)azetidine (85) using the procedure described for compound (9) (1.15 mg, 30%).

Sources & evidence

ORD record
ord-5acc3dc7ffe14abaaf8949ae68ceaac1
Source dataset
uspto-grants-2009_03
Patent number
US07504522B2

Reaction notes

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