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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1785659Generated: November 1, 2026

3-(2,4'-Dichlorobenzhydryloxy)azetidine hydrochloride → 3-[2-(Trifluoromethyl)-4'-chlorobenzhydryloxy]azetidine hydrochloride

https://huagongshe.com/reaction/1785659

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(2,4'-Dichlorobenzhydryloxy)azetidine hydrochlorideHCID 68902343—
Reactant1-Benzhydryl-3-[2-(trifluoromethyl)-4'-chlorobenzhydryloxy]azetidineHCID 68906138—
Product3-[2-(Trifluoromethyl)-4'-chlorobenzhydryloxy]azetidine hydrochlorideHCID 68902463—

Reaction Steps

This material was prepared from 1-benzhydryl-3-[2-(trifluoromethyl)-4′-chlorobenzhydryloxy]azetidine (97) (25.6 mmol) using the procedure described for compound (9) (8.2 g, 85%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07504522B2
Source datasetuspto-grants-2009_03
ORD IDord-d5a456fbf37b41c096141755c7d05d50
Source noteuspto-grants-2009_03