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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1785663Generated: October 31, 2026

Isocyanate → 3-[2-(trifluoromethyl)-4'-chlorobenzhydryloxy]-N-[(S)-alpha-methyl-benzyl]azetidine-1-carboxamide

https://huagongshe.com/reaction/1785663

Reaction equation

Participants

RoleNameHCIDCharge
ReactantIsocyanateHCID 105034—
Reactant3-[2-(Trifluoromethyl)-4'-chlorobenzhydryloxy]azetidine hydrochlorideHCID 68902463—
Product3-[2-(trifluoromethyl)-4'-chlorobenzhydryloxy]-N-[(S)-alpha-methyl-benzyl]azetidine-1-carboxamideHCID 11306353—

Reaction Steps

This material was prepared from 3-[2-(trifluoromethyl)-4′-chlorobenzhydryloxy]azetidine hydrochloride (98) and the corresponding isocyanate using the procedure described for compound (10).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07504522B2
Source datasetuspto-grants-2009_03
ORD IDord-6b640dd79e454835b4b48cb47c3df42b
Source noteuspto-grants-2009_03