Isocyanate → 3-(2,4'-dichlorobenzhydryloxy)-N-(2-methylbut-2-yl)azetidine-1-carboxamide

HRID 1785664Notes

Reaction equation

HRID 1785664 reaction equation
Cl.[Cl:2][C:3]1[CH:21]=[CH:20][CH:19]=[CH:18][C:4]=1[CH:5]([O:13][CH:14]1[CH2:17][NH:16][CH2:15]1)[C:6]1[CH:11]=[CH:10][C:9]([Cl:12])=[CH:8][CH:7]=1.[N-:22]=[C:23]=[O:24]>>[Cl:2][C:3]1[CH:21]=[CH:20][CH:19]=[CH:18][C:4]=1[CH:5]([O:13][CH:14]1[CH2:17][N:16]([C:23]([NH:22][C:4]([CH3:18])([CH2:3][CH3:21])[CH3:5])=[O:24])[CH2:15]1)[C:6]1[CH:7]=[CH:8][C:9]([Cl:12])=[CH:10][CH:11]=1

Participants

3

Reactant 2

HCID 105034IsocyanateHCID 689023433-(2,4'-Dichlorobenzhydryloxy)azetidine hydrochloride

Product 1

HCID 112930843-(2,4'-dichlorobenzhydryloxy)-N-(2-methylbut-2-yl)azetidine-1-carboxamide

Procedure

This material was prepared from 3-(2,4′-dichlorobenzhydryloxy)azetidine hydrochloride (9) and the corresponding isocyanate using the procedure described for compound (10).

Sources & evidence

ORD record
ord-dc5b01b877184e6bab67a1995351836d
Source dataset
uspto-grants-2009_03
Patent number
US07504522B2

Reaction notes

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