HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Bromo-2-fluorobenzaldehyde → 2-(Trifluoromethyl)-2'-fluoro-4'-bromobenzhydrol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Bromo-2-fluorobenzaldehyde | HCID 143517 | — |
| Reactant | (4-Chloro-2-(trifluoromethyl)phenyl)(phenyl)methanol | HCID 68907806 | — |
| Reactant | HCID 178506141 | HCID 178506141 | — |
| Product | 2-(Trifluoromethyl)-2'-fluoro-4'-bromobenzhydrol | HCID 63895852 | — |
Reaction Steps
This material was prepared from 2-(trifluoromethyl)phenylmagnesium bromide (60 mmol) and 4-bromo-2-fluorobenzaldehyde (54 mmol) using the procedure described for compound (96) (12.3 g, 74%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07504522B2 |
| Source dataset | uspto-grants-2009_03 |
| ORD ID | ord-dc45ad6a8f53427ba076493717fa957c |
| Source note | uspto-grants-2009_03 |