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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1785671Generated: October 30, 2026

3-(2,4'-Dichlorobenzhydryloxy)azetidine hydrochloride → 3-[2-Trifluoromethyl-4'-(methylthio)benzhydryloxy]azetidine hydrochloride

https://huagongshe.com/reaction/1785671

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(2,4'-Dichlorobenzhydryloxy)azetidine hydrochlorideHCID 68902343—
Reactant1-Benzhydryl-3-[2-(trifluoromethyl)-4'-(methylthio)-benzhydryloxy]azetidineHCID 68902538—
Product3-[2-Trifluoromethyl-4'-(methylthio)benzhydryloxy]azetidine hydrochlorideHCID 68904236—

Reaction Steps

This material was prepared from 1-benzhydryl-3-[2-(trifluoromethyl)-4′-(methylthio)benzhydryloxy]azetidine (117) (8.7 mmol) using the procedure described for compound (9) (2.29 g, 68%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07504522B2
Source datasetuspto-grants-2009_03
ORD IDord-c59e34abcd84451390d37be085dee1e1
Source noteuspto-grants-2009_03