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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1785673Generated: October 30, 2026

Isocyanate → 3-[2-(trifluoromethyl)-4'-(methylthio)benzhydryloxy]-N-(sec-butyl)-azetidine-1-carboxamide

https://huagongshe.com/reaction/1785673

Reaction equation

Participants

RoleNameHCIDCharge
ReactantIsocyanateHCID 105034—
Reactant3-[2-Trifluoromethyl-4'-(methylthio)benzhydryloxy]azetidine hydrochlorideHCID 68904236—
Product3-[2-(trifluoromethyl)-4'-(methylthio)benzhydryloxy]-N-(sec-butyl)-azetidine-1-carboxamideHCID 11236328—

Reaction Steps

This material was prepared from 3-[2-trifluoromethyl-4′-(methylthio)benzhydryloxy]azetidine hydrochloride (118) and the corresponding isocyanate using the procedure described for compound (10).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07504522B2
Source datasetuspto-grants-2009_03
ORD IDord-3ca1af8c1c7d481fa55baff37c9d67a2
Source noteuspto-grants-2009_03