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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1785675Generated: October 26, 2026

4-Fluoro-2-(trifluoromethyl)benzaldehyde → 2-(Trifluoromethyl)-4-fluoro-4'-chlorobenzhydrol

https://huagongshe.com/reaction/1785675

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Fluoro-2-(trifluoromethyl)benzaldehydeHCID 522940—
Reactant2,4,4'-TrichlorobenzhydrolHCID 22565435—
ReactantHCID 178478191HCID 178478191—
Product2-(Trifluoromethyl)-4-fluoro-4'-chlorobenzhydrolHCID 68907802—

Reaction Steps

This material was prepared from 4-chlorophenylmagnesium bromide (28.6 mmol) and 4-fluoro-2-(trifluoromethyl)benzaldehyde (26.0 mmol) using the procedure described for compound (2) (6.04 g, 76%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07504522B2
Source datasetuspto-grants-2009_03
ORD IDord-49b4dd7ebec8402a9268ee21bc27c2de
Source noteuspto-grants-2009_03