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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1785680Generated: October 25, 2026

Isocyanate → 3-[2-(trifluoromethyl)-4-fluoro-4'-chlorobenzhydryloxy]-N-(cyclohexyl)azetidine-1-carboxamide

https://huagongshe.com/reaction/1785680

Reaction equation

Participants

RoleNameHCIDCharge
ReactantIsocyanateHCID 105034—
Reactant3-[2-(Trifluoromethyl)-4-fluoro-4'-chlorobenzhydryloxy]azetidine hydrochlorideHCID 86611161—
Product3-[2-(trifluoromethyl)-4-fluoro-4'-chlorobenzhydryloxy]-N-(cyclohexyl)azetidine-1-carboxamideHCID 11202553—

Reaction Steps

This material was prepared 3-[2-(trifluoromethyl)-4-fluoro-4′-chlorobenzhydryloxy]azetidine hydrochloride (125) and the corresponding isocyanate using the procedure described for compound (10).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07504522B2
Source datasetuspto-grants-2009_03
ORD IDord-c2c7814042774eb5a59fdec7aea59ae3
Source noteuspto-grants-2009_03