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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1785701Generated: October 30, 2026

4-Methoxybenzaldehyde → 2-(Trifluoromethyl)-4'-methoxybenzhydrol

https://huagongshe.com/reaction/1785701

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-MethoxybenzaldehydeHCID 31244—
Reactant(4-Chloro-2-(trifluoromethyl)phenyl)(phenyl)methanolHCID 68907806—
ReactantHCID 178506141HCID 178506141—
Product2-(Trifluoromethyl)-4'-methoxybenzhydrolHCID 13309098—

Reaction Steps

This material was prepared from 2-(trifluoromethyl)phenylmagnesium bromide (16 mmol) and p-anisaldehyde (1.86 mL, 15 mmol) using the procedure described for compound (96) (4.34 g, 100%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07504522B2
Source datasetuspto-grants-2009_03
ORD IDord-5308aabd61c14dc5bd84e5dde926ff29
Source noteuspto-grants-2009_03