HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(Diphenylmethyl)azetidin-3-ol → Isohexane ethyl acetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(Diphenylmethyl)azetidin-3-ol | HCID 330448 | — |
| Reactant | 2-(Trifluoromethyl)-4'-methoxybenzhydrol | HCID 13309098 | — |
| Reactant | 1-Benzhydryl-3-(2,4,4'-trichlorobenzhydryloxy)azetidine | HCID 68903818 | — |
| Product | Isohexane ethyl acetate | HCID 21882781 | — |
Reaction Steps
This material was prepared from 1-benzhydryl-3-azetidinol (1) (7.5 mmol) and 2-(trifluoromethyl)-4′-methoxybenzhydrol (155) (15 mmol) using the procedure described for compound (3). Flash column chromatography [SiO2; ethyl acetate-iso-hexane (10:90→20:80)] afforded a pale yellow gum (2.73 g) which was used in the next step without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07504522B2 |
| Source dataset | uspto-grants-2009_03 |
| ORD ID | ord-08d6b79edd824fb482fa241695c35012 |
| Source note | uspto-grants-2009_03 |