Methyl 4-(4-tert-butyl-1-cyclohexen-1-yl)benzoate → HCID 22730084, compound

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Reaction Steps

A room temperature mixture of Example 5B (230 mg, 0.84 mmol) and 10% Pd/C (100 mg) in ethyl acetate (5 mL) was stirred under a hydrogen atmosphere for 3 hours, filtered through a pad of silica gel (10 g) with diethyl ether (10 mL), and concentrated to provide the desired product as a ˜2:1 mixture of diastereomers. MS (DCI) m/e 275 (M+H)+.

Provenance & Evidence