HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → (r)-3-(2-Nitro-4-sulfamoylphenylamino)-4-(phenylthio)butanoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Tert-butyl (3r)-3-((4-(aminosulfonyl)-2-nitrophenyl)amino)-4-(phenylthio)butanoate | HCID 11511079 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | (r)-3-(2-Nitro-4-sulfamoylphenylamino)-4-(phenylthio)butanoic acid | HCID 11683013 | — |
Reaction Steps
A mixture of Example 122D and 4M HCl in 1,4-dioxane (10 mL) was stirred at 50° C. for 5 hours and concentrated to provide the desired product. MS (ESI(+)) m/e 412 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07504512B2 |
| Source dataset | uspto-grants-2009_03 |
| ORD ID | ord-1f88f4818f0c4c6e86e5f66f4a453aa0 |
| Source note | uspto-grants-2009_03 |