Water → HCID 22730545, compound

Participants

Reaction Steps

A solution of 4-iodopyrazole (11.25 g, 6.44 mmol) in DMF (20 mL) at room temperature was treated with 60% NaH (271 mg, 6.77 mmol), stirred for 10 minutes, treated with 1-bromooctane (1.22 mL, 7.08 mmol), stirred for 30 minutes, poured into water, and extracted three times with ether/hexanes. The combined extracts were washed with water and brine, dried (MgSO4), filtered, and concentrated to provide the desired product. MS. (ESI(+)) m/e 307 (M+H)+.

Provenance & Evidence