HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-tert-Butyl 4-ethyl 4-methylpiperidine-1,4-dicarboxylate → Ethyl 4-methylpiperidine-4-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-tert-Butyl 4-ethyl 4-methylpiperidine-1,4-dicarboxylate | HCID 16218276 | — |
| Solvent | Hydrochloric Acid | HCID 313 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | Ethyl 4-methylpiperidine-4-carboxylate | HCID 19361805 | — |
Reaction Steps
A solution of Example 532B (2.1 g, 8.0 mmol) in 4M HCl in dioxane (10 mL) at room temperature was stirred for 3 hours and concentrated to provide the desired product. MS (DCI) mne 171 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07504512B2 |
| Source dataset | uspto-grants-2009_03 |
| ORD ID | ord-c9a185424ee24b58b45040fed79c6a82 |
| Source note | uspto-grants-2009_03 |