HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1786097Generated: October 29, 2026
Thionyl Chloride → 2-(chloromethyl)-1-methyl-1H-imidazole hydrochloride
https://huagongshe.com/reaction/1786097
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | (1-methyl-1H-imidazol-2-yl)methanol | HCID 573612 | — |
| Product | 2-(chloromethyl)-1-methyl-1H-imidazole hydrochloride | HCID 2795406 | 69% |
Reaction Steps
20 g (0.179 mol) of (1-methyl-1H-imidazol-2-yl)methanol were added to 25 ml of SOCl2 under stirring at 0° C. The solution obtained was refluxed for 30 min and then the excess SOCl2 removed under vacuum. The thus obtained residue was recrystallized from 45 ml of EtOH to give 20.5 g (69%) of 2-(chloromethyl)-1-methyl-1H-imidazole hydrochloride.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US07507688B2 |
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| Source dataset | uspto-grants-2009_03 |
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| ORD ID | ord-d675fd71c5f64e3aa5cff22a2210eb43 |
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| Source note | uspto-grants-2009_03 |
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