HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloroacrylonitrile → 2-Cyclopentyl-4-pyrimidinamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloroacrylonitrile | HCID 70198 | — |
| Reactant | Cyclopentanecarboximidamide hydrochloride | HCID 42614157 | — |
| Product | 2-Cyclopentyl-4-pyrimidinamine | HCID 45787581 | 25.9% |
Reaction Steps
This material was obtained in analogy to example 2, step A] via the alternative preparation method from cyclopentanecarboxamidine hydrochloride (CAS 68284-02-6) (500 mg) and 2-chloroacrylonitrile (324 mg) to give 2-cyclopentyl-pyrimidin-4-ylamine as an amorphous glass (142 mg). MS (ESI): 164.6 (MH+). This material was contaminated with several side products that could not be identified.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07507733B2 |
| Source dataset | uspto-grants-2009_03 |
| ORD ID | ord-ed006657a40f44eda58e4a60d4fc4091 |
| Source note | uspto-grants-2009_03 |