反应详情

To sodium 4-methoxyphenylsulfamate (10.0 g 44 mmol) suspended in benzene (100 mL) was added PCl5 (9.2 g, 44 mmol) cautiously. The mixture was slowly warmed up and refluxed for 15 hrs. After cooling to rt., the mixture was filtered through a pad of Celite and solvent was removed from filtrate to leave a brown oil as 4-methoxyphenylsulfamoyl chloride, which was used in the next step without further purification.

1. temperatureThe mixture was slowly warmed up and
2. temperaturerefluxed for 15 hrs
3. filtration, the mixture was filtered through a pad of Celite and solvent
4. customwas removed from filtrate