Ammonia → HCID 23024530, compound

HRID 1786166Notes

Reaction equation

HRID 1786166 reaction equation
[C:1]1(=[CH:6][C:7]#[N:8])[CH2:5][CH2:4][CH2:3][CH2:2]1.[NH3:9]>CO>[NH2:9][C:1]1([CH2:6][C:7]#[N:8])[CH2:5][CH2:4][CH2:3][CH2:2]1

Participants

4

Reactant 2

HCID 222AmmoniaHCID 79810Cyclopentylideneacetonitrile

Product 1

HCID 23024530HCID 23024530, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

A solution of 15.91 g (0.15 mol) of cyclopentylideneacetonitrile in 170 ml of an aqueous ammonia solution (29%) and 57 ml of methanol was heated at 100° C. in a sealed tube for 24 h. The reaction mixture was concentrated, and the residue was chromatographed on silica gel eluting with a mixture of dichloromethane/methanol in the proportions 90/10 to afford 12.15 g of the product as a colorless oil.

Workup

  1. concentrationThe reaction mixture was concentrated
  2. customthe residue was chromatographed on silica gel eluting with a mixture of dichloromethane/methanol in the proportions 90/10

Sources & evidence

ORD record
ord-1ba81659adf441e4a9a62d5919b20e8d
Source dataset
uspto-grants-2009_03
Patent number
US07507743B2

Reaction notes

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