2-Methoxyacetohydrazide → 9-Bromo-2-methoxymethyl-6H-[1,2,4]triazolo[1,5-c]quinazolin-5-one

Participants

Reaction Steps

As described for example 1a) (4-bromo-2-cyano-phenyl)-carbamic acid ethyl ester (19.9 g, 74.2 mmol) instead of (4-chloro-2-cyano-phenyl)-carbamic acid ethyl ester using methoxymethyl-carboxylic acid hydrazide instead of cyclopropane-carboxylic acid hydrazide, was converted to the title compound (21.1 g, 92%) which was obtained as a light yellow solid. MS: m/e=308.9/310.9 [M+H]+.

Provenance & Evidence