HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrazine hydrate (1:1) → 2-Ethyl-1H-imidazole-1-acetic acid hydrazide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrazine hydrate (1:1) | HCID 24654 | — |
| Reactant | HCID 61345551 | HCID 61345551 | — |
| Solvent | 1-Butanol | HCID 263 | — |
| Product | 2-Ethyl-1H-imidazole-1-acetic acid hydrazide | HCID 49949156 | 94% |
Reaction Steps
As described for example 112a, (2-ethyl-imidazol-1-yl)-acetic acid ethyl ester in butanol was reacted with hydrazine hydrate (1.2 equivalents) at 100° C. for 6 h. Evaporation of all volatiles and crystallization from methanol/diisopropylether afforded the title compound as a white solid (yield: 94%). MS: m/e=169.3 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07507729B2 |
| Source dataset | uspto-grants-2009_03 |
| ORD ID | ord-0e0afe34ff914098b8cee6118339d5a9 |
| Source note | uspto-grants-2009_03 |