HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl bromoacetate → HCID 67549569, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl bromoacetate | HCID 7748 | — |
| Reactant | Heptane | HCID 8900 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | HCID 178517701 | HCID 178517701 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | HCID 67549569 | HCID 67549569 | 55% |
Reaction Steps
As described for example 320a, 3-bromo-2-hydroxy-pyridine was reacted with ethyl bromoacetate and potassium carbonate. Extractive workup followed by chromatography (SiO2, heptane:ethyl acetate=100:0 to 50:50) afforded the title compound as a light yellow oil (yield: 55%), which was directly used in the next step.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07507729B2 |
| Source dataset | uspto-grants-2009_03 |
| ORD ID | ord-6db2cce419324c5cb504e5393ad45e68 |
| Source note | uspto-grants-2009_03 |