HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Boc-2-(3-amino-5-trifluoromethyl-phenoxymethyl)-pyrrolidine → 1-Boc-2-[3-[(2-Fluoro-pyridine-3-carbonyl)-amino]-5-trifluoromethyl-phenoxymethyl}-pyrrolidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Boc-2-(3-amino-5-trifluoromethyl-phenoxymethyl)-pyrrolidine | HCID 21959488 | — |
| Reactant | 1-Boc-4-[3-[(2-fluoro-pyridine-3-carbonyl)-amino]-5-trifluoromethyl-phenoxy}-piperidine | HCID 21959521 | — |
| Product | 1-Boc-2-[3-[(2-Fluoro-pyridine-3-carbonyl)-amino]-5-trifluoromethyl-phenoxymethyl}-pyrrolidine | HCID 21959577 | — |
Reaction Steps
1-Boc-2-{3-[(2-Fluoro-pyridine-3-carbonyl)-amino]-5-trifluoromethyl-phenoxymethyl}-pyrrolidine was prepared from 1-Boc-2-(3-amino-5-trifluoromethyl-phenoxymethyl)-pyrrolidine by a procedure similar to that described in the preparation of 1-Boc-4-{3-[(2-fluoro-pyridine-3-carbonyl)-amino]-5-trifluoromethyl-phenoxy}-piperidine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07507748B2 |
| Source dataset | uspto-grants-2009_03 |
| ORD ID | ord-facb0e23ce574bfe9a9cd300c9825163 |
| Source note | uspto-grants-2009_03 |