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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 1786460생성일: 2026년 10월 25일

1-(Cyclopropylcarbonyl)piperazine → [6-Bromo-5-(1-isopropyl-piperidin-4-yloxy)-1H-indol-2-yl]-(4-cyclopropanecarbonyl-piperazin-1-yl)-methanone

https://huagongshe.com/reaction/1786460

반응식

참여 물질

역할이름HCID투입량
반응물1-(Cyclopropylcarbonyl)piperazineHCID 2064235—
반응물6-bromo-5-(1-isopropyl-piperidin-4-yloxy)-1H-indole-2-carboxylic acid hydrochlorideHCID 67017930—
생성물[6-Bromo-5-(1-isopropyl-piperidin-4-yloxy)-1H-indol-2-yl]-(4-cyclopropanecarbonyl-piperazin-1-yl)-methanoneHCID 6856672748%

반응 단계

The title compound was synthesized in analogy to example 1, from 6-bromo-5-(1-isopropyl-piperidin-4-yloxy)-1H-indole-2-carboxylic acid hydrochloride (example 1, intermediate a) and 1-(cyclopropanecarbonyl)piperazine to afford the title compound as a light-yellow foam (48%).

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US07507736B2
출처 데이터셋uspto-grants-2009_03
ORD IDord-e69e3bf0f3a64f0d91ae797b41304377
출처 메모uspto-grants-2009_03