HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl chloroformate → 4-[5-(1-Isopropyl-piperidin-4-yloxy)-1H-indole-2-carbonyl]-piperazine-1-carboxylic acid methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl chloroformate | HCID 6586 | — |
| Reactant | [5-(1-isopropyl-piperidin-4-yloxy)-1H-indol-2-yl]-piperazin-1-yl-methanone dihydrochloride | HCID 68565070 | — |
| Product | 4-[5-(1-Isopropyl-piperidin-4-yloxy)-1H-indole-2-carbonyl]-piperazine-1-carboxylic acid methyl ester | HCID 68564764 | — |
Reaction Steps
The title compound was prepared in analogy to example 51, from [5-(1-isopropyl-piperidin-4-yloxy)-1H-indol-2-yl]-piperazin-1-yl-methanone dihydrochloride and methyl chloroformate. Light-yellow solid. MS (m/z): 429.3 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07507736B2 |
| Source dataset | uspto-grants-2009_03 |
| ORD ID | ord-87f57e94d60c439abf48c98e8adc4d43 |
| Source note | uspto-grants-2009_03 |