Potassium Cation → 2-(4-Benzyloxycarbonyl-2-methoxy-phenylamino)-4-chloro-5-trifluoromethyl-pyrimidine

HRID 178669Notes

Reaction equation

HRID 178669 reaction equation
[Cl:26][c:27]1[n:28][cH:29][c:30]([C:34]([F:35])([F:36])[F:37])[c:31]([Cl:33])[n:32]1.[K+:20].[K+:21].[NH2:1][c:2]1[c:3]([O:18][CH3:19])[cH:4][c:5]([C:6](=[O:7])[O:8][CH2:9][c:10]2[cH:11][cH:12][cH:13][cH:14][cH:15]2)[cH:16][cH:17]1.[O-:22][C:23]([O-:24])=[O:25].[O:38]1[CH2:39][CH2:40][O:41][CH2:42][CH2:43]1>>[NH:1]([c:2]1[c:3]([O:18][CH3:19])[cH:4][c:5]([C:6](=[O:7])[O:8][CH2:9][c:10]2[cH:11][cH:12][cH:13][cH:14][cH:15]2)[cH:16][cH:17]1)[c:27]1[n:28][cH:29][c:30]([C:34]([F:35])([F:36])[F:37])[c:31]([Cl:33])[n:32]1

Participants

6

Reactant 5

HCID 813Potassium Cation2×HCID 19660Carbonate IonHCID 312751,4-DioxaneHCID 27827742,4-Dichloro-5-(trifluoromethyl)pyrimidineHCID 58200992Benzyl 4-amino-3-methoxybenzoate

Product 1

HCID 582010032-(4-Benzyloxycarbonyl-2-methoxy-phenylamino)-4-chloro-5-trifluoromethyl-pyrimidine

Sources & evidence

ORD record
ord-039d2be355ff42b4818e335df18bf913
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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