HCID 57598517, compound → HCID 57598529, compound

HRID 1786836Notes

Reaction equation

HRID 1786836 reaction equation
[OH:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][CH2:9][NH:10][C:11](=[O:26])[CH:12]([O:16][C:17]2[CH:22]=[CH:21][C:20]([C:23]#[N:24])=[C:19]([Cl:25])[CH:18]=2)[CH2:13][CH2:14][CH3:15])=[CH:4][CH:3]=1>O>[OH:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][CH2:9][NH:10][C:11](=[O:26])[C@@H:12]([O:16][C:17]2[CH:22]=[CH:21][C:20]([C:23]#[N:24])=[C:19]([Cl:25])[CH:18]=2)[CH2:13][CH2:14][CH3:15])=[CH:4][CH:3]=1

Participants

3

Reactant 1

HCID 57598517HCID 57598517, compound

Product 1

HCID 57598529HCID 57598529, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

The product of Example 105 was prepared by chiral HPLC separation of the product of Example 103. MS: 373.1(M+1 for C20H21ClN2O3) LCMS: C-18 column (25% H2O/75% CH3CN. RT=0.91 min. Purity 99.9%

Sources & evidence

ORD record
ord-85d9833c49984f5a934011ac3929d0d0
Source dataset
uspto-grants-2009_03
Patent number
US07507860B2

Reaction notes

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