2-(Dimethylamino)ethanol → HCID 116947, compound

HRID 1786840Notes

Reaction equation

HRID 1786840 reaction equation
[CH3:1][N:2]([CH3:6])[CH2:3][CH2:4][OH:5].[C:7]1(=[O:13])[O:12][C:10](=[O:11])[CH2:9][CH2:8]1>N1C=CC=CC=1>[CH3:1][N:2]([CH3:6])[CH2:3][CH2:4][O:5][C:7](=[O:13])[CH2:8][CH2:9][C:10]([OH:12])=[O:11]

Participants

4

Reactant 2

HCID 79022-(Dimethylamino)ethanolHCID 7922Succinic anhydride

Product 1

HCID 116947HCID 116947, compound

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent2×

Procedure

The 2-dimethylamino ethanol (10 g, 0.11 mol) was dissolved in pyridine (100 mL) followed by the addition of succinic anhydride (16 g, 0.16 mol). The mixture was stirred at room temperature for 18 h before the pyridine was removed under vacuum at 40 C. The remaining solid was recrystallized from MeOH/Ether. The characterization data were consistent with the chemical structure and formula.

Workup

  1. customwas removed under vacuum at 40 C
  2. customThe remaining solid was recrystallized from MeOH/Ether

Sources & evidence

ORD record
ord-a4e7b23466d444d4849419c70ebb3bf1
Source dataset
uspto-grants-2009_03
Patent number
US07507859B2

Reaction notes

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