2,3,5-Trimethylphenol → 1-(3-Bromophenyl)-2-(2,3,5-trimethylphenoxy)ethanone

HRID 1787139Notes

Reaction equation

HRID 1787139 reaction equation
[CH3:1][C:2]1[C:7]([CH3:8])=[CH:6][C:5]([CH3:9])=[CH:4][C:3]=1[OH:10].Br[CH2:12][C:13]([C:15]1[CH:20]=[CH:19][CH:18]=[C:17]([Br:21])[CH:16]=1)=[O:14]>>[Br:21][C:17]1[CH:16]=[C:15]([C:13](=[O:14])[CH2:12][O:10][C:3]2[CH:4]=[C:5]([CH3:9])[CH:6]=[C:7]([CH3:8])[C:2]=2[CH3:1])[CH:20]=[CH:19][CH:18]=1

Participants

3

Reactant 2

HCID 127692,3,5-TrimethylphenolHCID 5195852-Bromo-1-(3-bromophenyl)ethan-1-one

Product 1

HCID 231140081-(3-Bromophenyl)-2-(2,3,5-trimethylphenoxy)ethanoneYield 52%

Procedure

Using 2,3,5-trimethylphenol and 2-bromo-1-(3-bromophenyl)ethanone, the title compound was synthesized in the same manner as in Reference Example 159. Yield 52%. Oily matter.

Sources & evidence

ORD record
ord-76328dece4224a42ac6d78dfe615c46b
Source dataset
uspto-grants-2009_03
Patent number
US07507841B2

Reaction notes

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