HCID 68711288, compound → HCID 68707332, compound

HRID 1787185Notes

Reaction equation

HRID 1787185 reaction equation
C([NH:8][C:9]1[C:10]([CH3:29])=[C:11]([CH2:19][C:20]2[CH:25]=[CH:24][C:23]([CH:26]([CH3:28])[CH3:27])=[CH:22][CH:21]=2)[C:12]2[O:16][CH2:15][CH2:14][C:13]=2[C:17]=1[CH3:18])C1C=CC=CC=1>C(OCC)(=O)C.CCCCCC>[CH:26]([C:23]1[CH:24]=[CH:25][C:20]([CH2:19][C:11]2[C:12]3[O:16][CH2:15][CH2:14][C:13]=3[C:17]([CH3:18])=[C:9]([NH2:8])[C:10]=2[CH3:29])=[CH:21][CH:22]=1)([CH3:28])[CH3:27]

Participants

3

Reactant 1

HCID 68711288HCID 68711288, compound

Product 1

HCID 68707332HCID 68707332, compoundYield 92%

Reagents, catalysts & solvents 1

HCID 21226206Ethyl acetate hexaneSolvent

Procedure

Using N-benzyl-7-(4-isopropylbenzyl)-4,6-dimethyl-2,3-dihydro-1-benzofuran-5-amine obtained in Reference Example 271, the title compound was synthesized in the same manner as in Reference Example 30. Yield 92%. Melting point: 114-115° C. (ethyl acetate-hexane).

Workup

  1. customobtained in Reference Example 271

Sources & evidence

ORD record
ord-298630fe7309428287c3f2bda68e20da
Source dataset
uspto-grants-2009_03
Patent number
US07507841B2

Reaction notes

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