HCID 68705468, compound → HCID 68709445, compound

HRID 1787196Notes

Reaction equation

HRID 1787196 reaction equation
C([NH:8][C:9]1[C:17]2[O:16][CH2:15][CH:14]([C:18]3[CH:23]=[CH:22][C:21]([CH:24]([CH3:26])[CH3:25])=[CH:20][CH:19]=3)[C:13]=2[C:12]([CH3:27])=[C:11]([CH3:28])[C:10]=1[CH3:29])C1C=CC=CC=1>CCCCCC.C(OCC)(=O)C>[CH:24]([C:21]1[CH:20]=[CH:19][C:18]([CH:14]2[C:13]3[C:12]([CH3:27])=[C:11]([CH3:28])[C:10]([CH3:29])=[C:9]([NH2:8])[C:17]=3[O:16][CH2:15]2)=[CH:23][CH:22]=1)([CH3:26])[CH3:25]

Participants

3

Reactant 1

HCID 68705468HCID 68705468, compound

Product 1

HCID 68709445HCID 68709445, compoundYield 80%

Reagents, catalysts & solvents 1

HCID 21226206Ethyl acetate hexaneSolvent

Procedure

Using N-benzyl-3-(4-isopropylphenyl)-4,5,6-trimethyl-2,3-dihydro-1-benzofuran-7-amine synthesized in Reference Example 287, the title compound was synthesized in the same manner as in Reference Example 30. Yield 80%. Melting point: 122-123° C. (hexane-ethyl acetate).

Workup

  1. customsynthesized in Reference Example 287

Sources & evidence

ORD record
ord-4b9cae309f4342609c0094b549683f5d
Source dataset
uspto-grants-2009_03
Patent number
US07507841B2

Reaction notes

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