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HRID1787242

反应详情

EQUATION

反应方程式

HRID 1787242 的结构方程式

REACTANTS

反应物

2
结构：CCCCCC.CCOC(C)=O
HCID21226206

未命名化合物

结构：Cc1c(Br)c2c(c(C)c1NC(=O)CC(C)(C)C)[C@@H](c1ccc(C(C)C)cc1)CO2
HCID68707779

未命名化合物

PRODUCTS

生成物

1
结构：COc1c(C)c(NC(=O)CC(C)(C)C)c(C)c2c1OC[C@@H]2c1ccc(C(C)C)cc1
HCID68705577

未命名化合物

收率 98%

AUXILIARIES

试剂、催化剂与溶剂

1
结构：ClC(Cl)Cl
溶剂HCID6212

Chloroform

CHCl3

PROCEDURE

实验过程

Using (−)-N-((3R)-7-bromo-3-(4-isopropylphenyl)-4,6-dimethyl-2,3-dihydro-1-benzofuran-5-yl)-3,3-dimethylbutanamide obtained in Example 51, the title compound was synthesized in the same manner as in Example 36. Yield: 98%. Melting point: 150-151° C. (ethyl acetate-hexane). [α]D20=+55.9° (c=0.50, chloroform).