Ethyl acetate hexane → HCID 23114078, compound

HRID 1787252Notes

Reaction equation

HRID 1787252 reaction equation
Br[C:2]1[C:7]2[CH:8]([C:11]3[CH:16]=[CH:15][C:14]([CH:17]([CH3:19])[CH3:18])=[CH:13][CH:12]=3)[CH2:9][O:10][C:6]=2[C:5]([CH3:20])=[C:4]([CH3:21])[C:3]=1[NH:22][C:23](=[O:29])[CH2:24][C:25]([CH3:28])([CH3:27])[CH3:26].CCCCCC.[C:36](OCC)(=[O:38])C>>[CH:17]([C:14]1[CH:15]=[CH:16][C:11]([CH:8]2[C:7]3[C:2]([O:38][CH3:36])=[C:3]([NH:22][C:23](=[O:29])[CH2:24][C:25]([CH3:28])([CH3:27])[CH3:26])[C:4]([CH3:21])=[C:5]([CH3:20])[C:6]=3[O:10][CH2:9]2)=[CH:12][CH:13]=1)([CH3:19])[CH3:18]

Participants

3

Reactant 2

HCID 21226206Ethyl acetate hexaneHCID 23113989HCID 23113989, compound

Product 1

HCID 23114078HCID 23114078, compoundYield 21%

Procedure

Using N-(4-bromo-3-(4-isopropylphenyl)-6,7-dimethyl-2,3-dihydro-1-benzofuran-5-yl)-3,3-dimethylbutanamide obtained in Example 63, the title compound was synthesized in the same manner as in Example 36. Yield: 21%. Melting point: 161-162° C. (hexane-ethyl acetate).

Sources & evidence

ORD record
ord-948dc36d5f504e2688fc34a3d7b5e4ca
Source dataset
uspto-grants-2009_03
Patent number
US07507841B2

Reaction notes

Loading…