Ethyl acetate hexane → HCID 23114262, compound

HRID 1787253Notes

Reaction equation

HRID 1787253 reaction equation
Br[C:2]1[C:19]([NH:20][C:21](=[O:27])[CH2:22][C:23]([CH3:26])([CH3:25])[CH3:24])=[C:18]([CH3:28])[C:5]2[CH:6]([C:9]3[CH:14]=[CH:13][C:12]([CH:15]([CH3:17])[CH3:16])=[CH:11][CH:10]=3)[CH2:7][O:8][C:4]=2[C:3]=1[CH3:29].CCCCCC.[C:36](OCC)(=[O:38])C>>[CH:15]([C:12]1[CH:11]=[CH:10][C:9]([CH:6]2[C:5]3[C:18]([CH3:28])=[C:19]([NH:20][C:21](=[O:27])[CH2:22][C:23]([CH3:24])([CH3:25])[CH3:26])[C:2]([O:38][CH3:36])=[C:3]([CH3:29])[C:4]=3[O:8][CH2:7]2)=[CH:14][CH:13]=1)([CH3:17])[CH3:16]

Participants

3

Reactant 2

HCID 21226206Ethyl acetate hexaneHCID 23113846HCID 23113846, compound

Product 1

HCID 23114262HCID 23114262, compoundYield 37%

Procedure

Using N-(6-bromo-3-(4-isopropylphenyl)-4,7-dimethyl-2,3-dihydro-1-benzofuran-5-yl)-3,3-dimethylbutanamide obtained in Example 87, the title compound was synthesized in the same manner as in Example 36. Yield: 37%. Melting point: 162-163° C. (hexane-ethyl acetate).

Sources & evidence

ORD record
ord-ef007c88dda746b9a10e9423698c2094
Source dataset
uspto-grants-2009_03
Patent number
US07507841B2

Reaction notes

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