HCID 23114210, compound → HCID 23114428, compound

HRID 1787258Notes

Reaction equation

HRID 1787258 reaction equation
O[CH:2]([C:31]1[CH:36]=[CH:35][C:34]([CH:37]([CH3:39])[CH3:38])=[CH:33][CH:32]=1)[C:3]1[C:11]2[O:10][CH2:9][CH:8]([C:12]3[CH:17]=[CH:16][C:15]([CH:18]([CH3:20])[CH3:19])=[CH:14][CH:13]=3)[C:7]=2[C:6]([CH3:21])=[C:5]([NH:22][C:23](=[O:29])[CH2:24][C:25]([CH3:28])([CH3:27])[CH3:26])[C:4]=1[CH3:30]>CCCCCC.C(OCC)(=O)C>[CH:37]([C:34]1[CH:35]=[CH:36][C:31]([CH2:2][C:3]2[C:11]3[O:10][CH2:9][CH:8]([C:12]4[CH:17]=[CH:16][C:15]([CH:18]([CH3:20])[CH3:19])=[CH:14][CH:13]=4)[C:7]=3[C:6]([CH3:21])=[C:5]([NH:22][C:23](=[O:29])[CH2:24][C:25]([CH3:28])([CH3:27])[CH3:26])[C:4]=2[CH3:30])=[CH:32][CH:33]=1)([CH3:38])[CH3:39]

Participants

3

Reactant 1

HCID 23114210HCID 23114210, compound

Product 1

HCID 23114428HCID 23114428, compoundYield 64%

Reagents, catalysts & solvents 1

HCID 21226206Ethyl acetate hexaneSolvent

Procedure

Using N-(7-(hydroxy(4-isopropylphenyl)methyl)-3-(4-isopropylphenyl)-4,6-dimethyl-2,3-dihydro-1-benzofuran-5-yl)-3,3-dimethylbutanamide obtained in Example 95, the title compound was synthesized in the same manner as in Example 96. Yield: 64%. Melting point: 157-158° C. (hexane-ethyl acetate).

Sources & evidence

ORD record
ord-b7c2cc32d4814478a5d0e71d53dbc04c
Source dataset
uspto-grants-2009_03
Patent number
US07507841B2

Reaction notes

Loading…