3-Nitrophenylboronic Acid → HCID 23114166, compound

HRID 1787270Notes

Reaction equation

HRID 1787270 reaction equation
Br[C:2]1[C:10]2[O:9][CH2:8][CH:7]([C:11]3[CH:16]=[CH:15][C:14]([CH:17]([CH3:19])[CH3:18])=[CH:13][CH:12]=3)[C:6]=2[C:5]([CH3:20])=[C:4]([NH:21][C:22](=[O:28])[CH2:23][C:24]([CH3:27])([CH3:26])[CH3:25])[C:3]=1[CH3:29].[N+:30]([C:33]1[CH:34]=[C:35](B(O)O)[CH:36]=[CH:37][CH:38]=1)([O-:32])=[O:31]>>[N+:30]([C:33]1[CH:38]=[C:37]([C:2]2[C:10]3[O:9][CH2:8][CH:7]([C:11]4[CH:16]=[CH:15][C:14]([CH:17]([CH3:19])[CH3:18])=[CH:13][CH:12]=4)[C:6]=3[C:5]([CH3:20])=[C:4]([NH:21][C:22](=[O:28])[CH2:23][C:24]([CH3:25])([CH3:26])[CH3:27])[C:3]=2[CH3:29])[CH:36]=[CH:35][CH:34]=1)([O-:32])=[O:31]

Participants

3

Reactant 2

HCID 16773-Nitrophenylboronic AcidHCID 23113867N-(7-Bromo-3-(4-isopropylphenyl)-4,6-dimethyl-2,3-dihydro-1-benzofuran-5-yl)-3,3-dimethylbutanamide

Product 1

HCID 23114166HCID 23114166, compoundYield 59%

Procedure

Using N-(7-bromo-3-(4-isopropylphenyl)-4,6-dimethyl-2,3-dihydro-1-benzofuran-5-yl)-3,3-dimethylbutanamide obtained in Example 35 and (3-nitrophenyl)boronic acid, the title compound was obtained in the same manner as in Example 107. Yield: 59%. Melting point: 209-210° C. (ethyl acetate-hexane).

Sources & evidence

ORD record
ord-a19b12829f8841dbb6b24494b490f7d8
Source dataset
uspto-grants-2009_03
Patent number
US07507841B2

Reaction notes

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