Ethanolamine → HCID 23114109, compound

HRID 1787296Notes

Reaction equation

[CH:1]([C:4]1[CH:9]=[CH:8][C:7]([CH:10]2[C:14]3[C:15]([CH3:30])=[C:16]([NH:21][C:22](=[O:29])OCC(Cl)(Cl)Cl)[C:17]([CH3:20])=[C:18]([CH3:19])[C:13]=3[O:12][CH2:11]2)=[CH:6][CH:5]=1)([CH3:3])[CH3:2].[OH:31][CH2:32][CH2:33][NH2:34]>>[OH:31][CH2:32][CH2:33][NH:34][C:22]([NH:21][C:16]1[C:17]([CH3:20])=[C:18]([CH3:19])[C:13]2[O:12][CH2:11][CH:10]([C:7]3[CH:6]=[CH:5][C:4]([CH:1]([CH3:2])[CH3:3])=[CH:9][CH:8]=3)[C:14]=2[C:15]=1[CH3:30])=[O:29]

Participants

Reactant 2

HCID 700Ethanolamine

HCID 86618058HCID 86618058, compound

Product 1

HCID 23114109HCID 23114109, compoundYield 89%

Procedure

Using 2,2,2-trichloroethyl (3-(4-isopropylphenyl)-4,6,7-trimethyl-2,3-dihydro-1-benzofuran-5-yl)carbamate obtained in Example 138 and 2-hydroxyethylamine, the title compound was obtained in the same manner as in Example 143.

Sources & evidence

ORD record: ord-205a6d0b740449438047020adbd8edc2
Source dataset: uspto-grants-2009_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07507841B2

Reaction notes

Loading…