Ethanolamine → HCID 23114031, compound

HRID 1787299Notes

Reaction equation

HRID 1787299 reaction equation
[CH2:1]([C:3]1[C:11]2[O:10][CH2:9][CH:8]([C:12]3[CH:17]=[CH:16][C:15]([CH:18]([CH3:20])[CH3:19])=[CH:14][CH:13]=3)[C:7]=2[C:6]([CH3:21])=[C:5]([NH:22][C:23](=[O:30])OCC(Cl)(Cl)Cl)[C:4]=1[CH3:31])[CH3:2].[NH2:32][CH2:33][CH2:34][OH:35]>CCCCCC.C(OCC)(=O)C>[CH2:1]([C:3]1[C:11]2[O:10][CH2:9][CH:8]([C:12]3[CH:17]=[CH:16][C:15]([CH:18]([CH3:20])[CH3:19])=[CH:14][CH:13]=3)[C:7]=2[C:6]([CH3:21])=[C:5]([NH:22][C:23]([NH:32][CH2:33][CH2:34][OH:35])=[O:30])[C:4]=1[CH3:31])[CH3:2]

Participants

4

Reactant 2

HCID 700EthanolamineHCID 86618059HCID 86618059, compound

Product 1

HCID 23114031HCID 23114031, compoundYield 57%

Reagents, catalysts & solvents 1

HCID 21226206Ethyl acetate hexaneSolvent

Procedure

Using 2,2,2-trichloroethyl (7-ethyl-3-(4-isopropylphenyl)-4,6-dimethyl-2,3-dihydro-1-benzofuran-5-yl)carbamate obtained in Example 139 and 2-aminoethanol, the title compound was synthesized in the same manner as in Example 143. Yield: 57%. Melting point: 147-148° C. (hexane-ethyl acetate).

Sources & evidence

ORD record
ord-ce9cdda876094bd68092140ba0e7d18a
Source dataset
uspto-grants-2009_03
Patent number
US07507841B2

Reaction notes

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